Photodynamic Therapy of Recalcitrant Warts with 5-Aminolevulinic Acid: A Retrospective Analysis

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Photodynamic therapy of recalcitrant warts with 5-aminolevulinic acid: a retrospective analysis.

Sir, Photodynamic therapy (PDT) with topical application of 5aminolevulinic acid (ALA) has been successful in the treatment of super®cial non-melanoma skin tumours (1). When applied topically to the skin, ALA is absorbed into the epidermal cells and biosynthesized to the light-sensitive metabolite photoporphyrin IX (PpIX). When cells with accumulated PpIX are exposed to light of certain wavelen...

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Photodynamic therapy (PDT) is a clinical treatment that combines the effects of visible light irradiation with subsequent biochemical events that arise from the presence of a photosensitising drug (possessing no dark toxicity) to cause destruction of selected cells. Today, the most common agent used in dermatological PDT is 5-aminolevulinic acid (ALA). As a result of its hydrophilic character, ...

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ژورنال

عنوان ژورنال: Acta Dermato-Venereologica

سال: 1999

ISSN: 0001-5555

DOI: 10.1080/000155599750010463